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Dried Blood Spot Technique-Based Liquid Chromatography-Tandem Mass Spectrometry Method as a Simple Alternative for Benznidazole Pharmacokinetic Assessment

Chagas disease (CD) is recognized as one of the major neglected global tropical diseases. Benznidazole (BNZ) is the drug of choice for the treatment of adults, young infants, and newborns with CD. However, the pharmacokinetics (PK) of BNZ have been poorly evaluated in all age groups, with consequent...

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Detalles Bibliográficos
Autores principales: Galindo Bedor, Danilo César, Tavares Cavalcanti Bedor, Noely Camila, Viturino da Silva, José Wellithom, Damasceno Sousa, Giovana, Pereira de Santana, Davi, Garcia-Bournissen, Facundo, Altcheh, Jaime, Blum, Bethania, Alves, Fabiana, Ribeiro, Isabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256767/
https://www.ncbi.nlm.nih.gov/pubmed/30275095
http://dx.doi.org/10.1128/AAC.00845-18