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Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab
B cell activating factor of the TNF family (BAFF, also known as BLyS), a cytokine that regulates homeostasis of peripheral B cells, is elevated in the circulation of patients with autoimmune diseases such as systemic lupus erythematosus (SLE). BAFF is synthetized as a membrane-bound protein that can...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256835/ https://www.ncbi.nlm.nih.gov/pubmed/30524439 http://dx.doi.org/10.3389/fimmu.2018.02698 |