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Severe Embryotoxicity of Artemisinin Derivatives in Experimental Animals, but Possibly Safe in Pregnant Women
Preclinical studies in rodents have demonstrated that artemisinins, especially injectable artesunate, can induce fetal death and congenital malformations at a low dose range. The embryotoxicity can be induced in those animals only within a narrow window in early embryogenesis. Evidence was presented...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Molecular Diversity Preservation International
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256922/ https://www.ncbi.nlm.nih.gov/pubmed/20110870 http://dx.doi.org/10.3390/molecules15010040 |