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Synergistic Chondroprotective Effect of α-Tocopherol, Ascorbic Acid, and Selenium as well as Glucosamine and Chondroitin on Oxidant Induced Cell Death and Inhibition of Matrix Metalloproteinase-3—Studies in Cultured Chondrocytes

Overproduction of reactive oxygen species and impaired antioxidant defence accompanied by chronic inflammatory processes may impair joint health. Pro‑inflammatory cytokines such as interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α) stimulate the expression of metalloproteinases which deg...

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Detalles Bibliográficos
Autores principales: Graeser, Anne-Christin, Giller, Katrin, Wiegand, Heike, Barella, Luca, Boesch‑Saadatmandi, Christine, Rimbach, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256990/
https://www.ncbi.nlm.nih.gov/pubmed/20110869
http://dx.doi.org/10.3390/molecules15010027