Natural products as new antimitotic compounds for anticancer drug development

Cell cycle control genes are frequently mutated in cancer cells, which usually display higher rates of proliferation than normal cells. Dysregulated mitosis leads to genomic instability, which contributes to tumor progression and aggressiveness. Many drugs that disrupt mitosis have been studied beca...

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Detalles Bibliográficos
Autores principales: Paier, Carlos Roberto Koscky, Maranhão, Sarah Sant'Anna, Carneiro, Teiliane Rodrigues, Lima, Lídia Moreira, Rocha, Danilo Damasceno, da Silva Santos, Renan, de Farias, Kaio Moraes, de Moraes-Filho, Manoel Odorico, Pessoa, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256996/
https://www.ncbi.nlm.nih.gov/pubmed/30540125
http://dx.doi.org/10.6061/clinics/2018/e813s

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256996/
https://www.ncbi.nlm.nih.gov/pubmed/30540125
http://dx.doi.org/10.6061/clinics/2018/e813s

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