Synthesis and Vasorelaxant and Platelet Antiaggregatory Activities of a New Series of 6-Halo-3-phenylcoumarins †

A series of 6-halo-3-hydroxyphenylcoumarins (resveratrol-coumarins hybrid derivatives) was synthesized in good yields by a Perkin reaction followed by hydrolysis. The new compounds were evaluated for their vasorelaxant activity in intact rat aorta rings pre-contracted with phenylephrine (PE), as wel...

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Detalles Bibliográficos
Autores principales: Quezada, Elías, Delogu, Giovanna, Picciau, Carmen, Santana, Lourdes, Podda, Gianni, Borges, Fernanda, García-Morales, Verónica, Viña, Dolores, Orallo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257048/
https://www.ncbi.nlm.nih.gov/pubmed/20110890
http://dx.doi.org/10.3390/molecules15010270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257048/
https://www.ncbi.nlm.nih.gov/pubmed/20110890
http://dx.doi.org/10.3390/molecules15010270

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