Elucidating the Structure-Activity Relationships of the Vasorelaxation and Antioxidation Properties of Thionicotinic Acid Derivatives

Nicotinic acid, known as vitamin B(3), is an effective lipid lowering drug and intense cutaneous vasodilator. This study reports the effect of 2-(1-adamantylthio)nicotinic acid (6) and its amide 7 and nitrile analog 8 on phenylephrine-induced contraction of rat thoracic aorta as well as antioxidativ...

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Detalles Bibliográficos
Autores principales: Prachayasittikul, Supaluk, Wongsawatkul, Orapin, Worachartcheewan, Apilak, Nantasenamat, Chanin, Ruchirawat, Somsak, Prachayasittikul, Virapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257051/
https://www.ncbi.nlm.nih.gov/pubmed/20110883
http://dx.doi.org/10.3390/molecules15010198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257051/
https://www.ncbi.nlm.nih.gov/pubmed/20110883
http://dx.doi.org/10.3390/molecules15010198

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