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An Efficient, Mild and Solvent-Free Synthesis of Benzene Ring Acylated Harmalines
A facile synthesis of a series of benzene ring acylated analogues of harmaline has been achieved by Friedel-Crafts acylation under solvent-free conditions at room temperature using acyl halides/acid anhydrides and AlCl(3). The reaction afforded 10- and 12-acyl analogues of harmaline in good yield, a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257112/ https://www.ncbi.nlm.nih.gov/pubmed/20110872 http://dx.doi.org/10.3390/molecules15010068 |