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An Efficient, Mild and Solvent-Free Synthesis of Benzene Ring Acylated Harmalines

A facile synthesis of a series of benzene ring acylated analogues of harmaline has been achieved by Friedel-Crafts acylation under solvent-free conditions at room temperature using acyl halides/acid anhydrides and AlCl(3). The reaction afforded 10- and 12-acyl analogues of harmaline in good yield, a...

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Detalles Bibliográficos
Autores principales: Begum, Sabira, Zubair, Farhat, Nawazish Ali, Syed, Shaheen Siddiqui, Bina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257112/
https://www.ncbi.nlm.nih.gov/pubmed/20110872
http://dx.doi.org/10.3390/molecules15010068

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