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Norcoclaurine Synthase: Mechanism of an Enantioselective Pictet-Spengler Catalyzing Enzyme

The use of bifunctional catalysts in organic synthesis finds inspiration in the selectivity of enzymatic catalysis which arises from the specific interactions between basic and acidic amino acid residues and the substrate itself in order to stabilize developing charges in the transition state. Many...

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Detalles Bibliográficos
Autores principales: Bonamore, Alessandra, Barba, Marco, Botta, Bruno, Boffi, Alberto, Macone, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257185/
https://www.ncbi.nlm.nih.gov/pubmed/20428026
http://dx.doi.org/10.3390/molecules15042070