Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced Neurotoxicity

Aberrant or chronic microglial activation is strongly implicated in neurodegeneration, where prolonged induction of classical inflammatory pathways may lead to a compromised blood-brain barrier (BBB) or vasculature, features of many neurodegenerative disorders and implicated in the observed cognitiv...

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Detalles Bibliográficos
Autores principales: Piers, Thomas M., East, Emma, Villegas-Llerena, Claudio, Sevastou, Ioanna G., Matarin, Mar, Hardy, John, Pocock, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257202/
https://www.ncbi.nlm.nih.gov/pubmed/30524237
http://dx.doi.org/10.3389/fncel.2018.00404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257202/
https://www.ncbi.nlm.nih.gov/pubmed/30524237
http://dx.doi.org/10.3389/fncel.2018.00404

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