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Soluble Fibrinogen Triggers Non-cell Autonomous ER Stress-Mediated Microglial-Induced Neurotoxicity
Aberrant or chronic microglial activation is strongly implicated in neurodegeneration, where prolonged induction of classical inflammatory pathways may lead to a compromised blood-brain barrier (BBB) or vasculature, features of many neurodegenerative disorders and implicated in the observed cognitiv...
Autores principales: | Piers, Thomas M., East, Emma, Villegas-Llerena, Claudio, Sevastou, Ioanna G., Matarin, Mar, Hardy, John, Pocock, Jennifer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257202/ https://www.ncbi.nlm.nih.gov/pubmed/30524237 http://dx.doi.org/10.3389/fncel.2018.00404 |
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