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Bifunctional Catalysis: Direct Reductive Amination of Aliphatic Ketones with an Iridium-Phosphate Catalyst †

Chiral amines are one of the ubiquitous functional groups in fine chemical, pharmaceutical and agrochemical products, and the most convenient, economical, and eco-benign synthetic pathway to these amines is direct asymmetric reductive amination (DARA) of prochiral ketones. This paper shows that a wi...

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Detalles Bibliográficos
Autores principales: Villa-Marcos, Barbara, Li, Chaoqun, Mulholland, Keith R., Hogan, Philip J., Xiao, Jianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257260/
https://www.ncbi.nlm.nih.gov/pubmed/20428055
http://dx.doi.org/10.3390/molecules15042453