Synthesis of syn-γ-Amino-β-hydroxyphosphonates by Reduction of β-Ketophosphonates Derived from L-Proline and L-Serine

The reduction of γ-N-benzylamino-β-ketophosphonates 6 and 10, readily available from L-proline and L-serine, respectively, can be carried out in high diastereoselectivity with catecholborane (CB) in THF at -78 °C to produce the syn-γ-N-benzylamino-β-hydroxyphosphonates 11 and 13 as a single detectab...

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Detalles Bibliográficos
Autores principales: Ordóñez, Mario, Lagunas-Rivera, Selene, Hernández-Núñez, Emanuel, Labastida-Galván, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257292/
https://www.ncbi.nlm.nih.gov/pubmed/20335981
http://dx.doi.org/10.3390/molecules15031291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257292/
https://www.ncbi.nlm.nih.gov/pubmed/20335981
http://dx.doi.org/10.3390/molecules15031291

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