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Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines

Development of novel therapy strategies is one of the major pressing topics of clinical oncology to overcome drug resistance of tumors. Artesunate (ART) is an anti-malarial drug, which also exerts profound cytotoxic activity towards cancer cells. We applied a gene-hunting approach using microarray-b...

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Detalles Bibliográficos
Autores principales: Sertel, Serkan, Eichhorn, Tolga, Simon, Christian H., Plinkert, Peter K., Johnson, Steven W., Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257326/
https://www.ncbi.nlm.nih.gov/pubmed/20428086
http://dx.doi.org/10.3390/molecules15042886