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Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines
Development of novel therapy strategies is one of the major pressing topics of clinical oncology to overcome drug resistance of tumors. Artesunate (ART) is an anti-malarial drug, which also exerts profound cytotoxic activity towards cancer cells. We applied a gene-hunting approach using microarray-b...
Autores principales: | Sertel, Serkan, Eichhorn, Tolga, Simon, Christian H., Plinkert, Peter K., Johnson, Steven W., Efferth, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257326/ https://www.ncbi.nlm.nih.gov/pubmed/20428086 http://dx.doi.org/10.3390/molecules15042886 |
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