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Pyridine-Based Heterocycles. Synthesis of New Pyrido [4',3':4,5]thieno[2,3-d]pyrimidines and Related Heterocycles

The synthesis of the title compounds was achieved using ethyl 2-amino-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (1) as starting material. The reaction of the amino ester 1 with phenylisothiocyanate in boiling ethanol afforded the thiourea derivative 5. The cyclization reactions...

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Detalles Bibliográficos
Autores principales: El-Kashef, Hussein, Farghaly, Abdel-Rahman, Al-Hazmi, Ahmed, Terme, Thierry, Vanelle, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257348/
https://www.ncbi.nlm.nih.gov/pubmed/20428071
http://dx.doi.org/10.3390/molecules15042651