Synthesis of N-(Methoxycarbonylthienylmethyl)thioureas and Evaluation of Their Interaction with Inducible and Neuronal Nitric Oxide Synthase

Two isomeric N-(methoxycarbonylthienylmethyl)thioureas were synthesised by a sequence of radical bromination of methylthiophenecarboxylic esters, substitution with trifluoroacetamide anion, deprotection, formation of the corresponding isothiocyanates and addition of ammonia. The interaction of these...

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Detalles Bibliográficos
Autores principales: Suaifan, Ghadeer A.R.Y., Goodyer, Claire L.M., Threadgill, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257465/
https://www.ncbi.nlm.nih.gov/pubmed/20657467
http://dx.doi.org/10.3390/molecules15053121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257465/
https://www.ncbi.nlm.nih.gov/pubmed/20657467
http://dx.doi.org/10.3390/molecules15053121

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