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Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β-amyloid production and tau hyperphosphorylation

β-amyloid (Aβ) aggregation and tau hyperphosphorylation are considered to be the primary pathological hallmarks of Alzheimer's disease (AD). Targeted inhibition of these pathological processes may provide effective treatments for AD. Accumulating evidence has demonstrated that ellagic acid (EA)...

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Detalles Bibliográficos
Autores principales: Zhong, Lili, Liu, Hong, Zhang, Weijia, Liu, Xu, Jiang, Bo, Fei, Hongxin, Sun, Zhongren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257515/
https://www.ncbi.nlm.nih.gov/pubmed/30542451
http://dx.doi.org/10.3892/etm.2018.6860