Cargando…

Ellagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β-amyloid production and tau hyperphosphorylation

β-amyloid (Aβ) aggregation and tau hyperphosphorylation are considered to be the primary pathological hallmarks of Alzheimer's disease (AD). Targeted inhibition of these pathological processes may provide effective treatments for AD. Accumulating evidence has demonstrated that ellagic acid (EA)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Lili, Liu, Hong, Zhang, Weijia, Liu, Xu, Jiang, Bo, Fei, Hongxin, Sun, Zhongren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257515/ https://www.ncbi.nlm.nih.gov/pubmed/30542451 http://dx.doi.org/10.3892/etm.2018.6860

Ejemplares similares

Cornel iridoid glycoside ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by attenuating amyloid-beta, tau hyperphosphorylation and neurotrophic dysfunction
por: Yang, Cuicui, et al.
Publicado: (2020)

Fuzheng Quxie Decoction Ameliorates Learning and Memory Impairment in SAMP8 Mice by Decreasing Tau Hyperphosphorylation
por: Yang, Yang, et al.
Publicado: (2017)

FLZ Alleviates the Memory Deficits in Transgenic Mouse Model of Alzheimer’s Disease via Decreasing Beta-Amyloid Production and Tau Hyperphosphorylation
por: Bao, Xiu-Qi, et al.
Publicado: (2013)

Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A
por: Liu, Jin, et al.
Publicado: (2016)

(-)-Epigallocatechin-3-gallate ameliorates learning and memory impairments by attenuating peroxidation in APP/PS1 transgenic mice
por: Liu, Mingyan, et al.
Publicado: (2012)

Immunological memory to hyperphosphorylated tau in asymptomatic individuals
por: Pascual, Gabriel, et al.
Publicado: (2017)

Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss
por: Tiwari, Sachin Suresh, et al.
Publicado: (2016)

Hyperphosphorylation-Induced Tau Oligomers
por: Iqbal, Khalid, et al.
Publicado: (2013)

Long-term depression links amyloid-β to the pathological hyperphosphorylation of tau
por: Taylor, Henry B.C., et al.
Publicado: (2021)

β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice
por: Sudduth, Tiffany L, et al.
Publicado: (2014)

Ligustilide Ameliorates Memory Deficiency in APP/PS1 Transgenic Mice via Restoring Mitochondrial Dysfunction
por: Xu, Yi-Jun, et al.
Publicado: (2018)

DNA vaccines targeting amyloid-β oligomer ameliorate cognitive deficits of aged APP/PS1/tau triple-transgenic mouse models of Alzheimer’s disease
por: Sha, Sha, et al.
Publicado: (2022)

Kainic acid hyperphosphorylates tau via inflammasome activation in MAPT transgenic mice
por: Zheng, Xiang-Yu, et al.
Publicado: (2019)

Qingxin kaiqiao fang ameliorates memory impairment and inhibits apoptosis in APP/PS1 double transgenic mice through the MAPK pathway
por: Gao, Shiyu, et al.
Publicado: (2019)

Codonopsis pilosula Polysaccharide Attenuates Tau Hyperphosphorylation and Cognitive Impairments in hTau Infected Mice
por: Zhang, Qing, et al.
Publicado: (2018)

Blockage of AEP attenuates TBI-induced tau hyperphosphorylation and cognitive impairments in rats
por: Liu, Yi, et al.
Publicado: (2020)

Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling
por: Li, Lei, et al.
Publicado: (2020)

Memory deficiency, cerebral amyloid angiopathy, and amyloid-β plaques in APP+PS1 double transgenic rat model of Alzheimer’s disease
por: Klakotskaia, Diana, et al.
Publicado: (2018)

Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease
por: Pascoal, T A, et al.
Publicado: (2017)

Indirubin-3′-monoxime suppresses amyloid-beta-induced apoptosis by inhibiting tau hyperphosphorylation
por: Zhang, Shu-gang, et al.
Publicado: (2016)

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice
por: Dickey, Chad A, et al.
Publicado: (2005)

Amelioration of Hippocampal Insulin Resistance Reduces Tau Hyperphosphorylation and Cognitive Decline Induced by Isoflurane in Mice
por: Peng, Liangyu, et al.
Publicado: (2021)

Autophagic Degradation Deficit Involved in Sevoflurane-Induced Amyloid Pathology and Spatial Learning Impairment in APP/PS1 Transgenic Mice
por: Geng, Pengcheng, et al.
Publicado: (2018)

Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid
por: Li, Yuanyuan, et al.
Publicado: (2016)

Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies
por: Li, Cong, et al.
Publicado: (2017)

Altered filamin A enables amyloid beta-induced tau hyperphosphorylation and neuroinflammation in Alzheimer’s disease
por: Burns, Lindsay H., et al.
Publicado: (2017)

Activated gliosis, accumulation of amyloid β, and hyperphosphorylation of tau in aging canines with and without cognitive decline
por: Hines, Amelia D., et al.
Publicado: (2023)

Reduction of kinesin I heavy chain decreases tau hyperphosphorylation, aggregation, and memory impairment in Alzheimer’s disease and tauopathy models
por: Selvarasu, Karthikeyan, et al.
Publicado: (2022)

Erratum: Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid
por: Li, Yuanyuan, et al.
Publicado: (2016)

Correction for: Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid
por: Li, Yuanyuan, et al.
Publicado: (2023)

Mitochondrial Oxidative Stress Causes Hyperphosphorylation of Tau
por: Melov, Simon, et al.
Publicado: (2007)

Hyperphosphorylated tau in young and middle-aged subjects
por: Elobeid, Adila, et al.
Publicado: (2011)

PINCH in the Cellular Stress Response to Tau-Hyperphosphorylation
por: Ozdemir, Ahmet Yunus, et al.
Publicado: (2013)

Oligomer Formation of Tau Protein Hyperphosphorylated in Cells
por: Tepper, Katharina, et al.
Publicado: (2014)

Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice
por: Xu, Longfei, et al.
Publicado: (2022)

Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer’s Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated
por: Barthélemy, Nicolas R., et al.
Publicado: (2022)

Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model
por: Yang, Seung-Hoon, et al.
Publicado: (2015)

Ketamine induces tau hyperphosphorylation at serine 404 in the hippocampus of neonatal rats
por: Jin, Haiyan, et al.
Publicado: (2013)

Naringin Dihydrochalcone Ameliorates Cognitive Deficits and Neuropathology in APP/PS1 Transgenic Mice
por: Yang, Wenjuan, et al.
Publicado: (2018)

Neuronal Deposition of Amyloid-β Oligomers and Hyperphosphorylated Tau Is Closely Connected with Cognitive Dysfunction in Aged Dogs
por: Habiba, Umma, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gdcbvc6g3m4dsfjfr3jlk2thqg