Solid-Phase Synthesis of New Trp(Nps)-Containing Dipeptide Derivatives as TRPV1 Channel Blockers

Trp(Nps)-Lys-NH(2) derivatives, bearing alkyl or guanidine groups either at the N–terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.

Detalles Bibliográficos
Autores principales: de Vega, Mª Jesús Pérez, García-López, Mª Teresa, Zaccaro, Laura, Royo, Miriam, Albericio, Fernando, Fernández-Carvajal, Asia, Ferrer-Montiel, Antonio, González-Muñiz, Rosario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257583/
https://www.ncbi.nlm.nih.gov/pubmed/20657400
http://dx.doi.org/10.3390/molecules15074924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257583/
https://www.ncbi.nlm.nih.gov/pubmed/20657400
http://dx.doi.org/10.3390/molecules15074924

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