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Solid-Phase Synthetic Route to Multiple Derivatives of a Fundamental Peptide Unit

Amino acids are Nature’s combinatorial building blocks. When substituted on both the amino and carboxyl sides they become the basic scaffold present in all peptides and proteins. We report a solid-phase synthetic route to large combinatorial variations of this fundamental scaffold, extending the var...

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Detalles Bibliográficos
Autores principales: Scott, William L., Zhou, Ziniu, Zajdel, Paweł, Pawłowski, Maciej, O’Donnell, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257617/
https://www.ncbi.nlm.nih.gov/pubmed/20657403
http://dx.doi.org/10.3390/molecules15074961