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Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs

[Image: see text] A series of dinuclear octahedral Pt(IV) complexes trans,trans,trans-[{Pt(N(3))(2)(py)(2)(OH)(OC(O)CH(2)CH(2)C(O)NH)}(2)R] containing pyridine (py) and bridging dicarboxylate [R = −CH(2)CH(2)– (1), trans-1,2-C(6)H(10)– (2), p-C(6)H(4)– (3), −CH(2)CH(2)CH(2)CH(2)– (4)] ligands have b...

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Detalles Bibliográficos
Autores principales: Shi, Huayun, Romero-Canelón, Isolda, Hreusova, Monika, Novakova, Olga, Venkatesh, V., Habtemariam, Abraha, Clarkson, Guy J., Song, Ji-inn, Brabec, Viktor, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257630/
https://www.ncbi.nlm.nih.gov/pubmed/30365308
http://dx.doi.org/10.1021/acs.inorgchem.8b02599