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A Therapeutic Approach to Nasopharyngeal Carcinomas by DNAzymes Targeting EBV LMP-1 Gene

Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has been known to have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC). Genetic manipulation of LMP1 expression may provide a novel strategy for the treatment of NPC. DNAzymes are synthetic, single-stran...

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Detalles Bibliográficos
Autores principales: Yang, Lifang, Lu, Zhongxin, Ma, Xiaoqian, Cao, Ya, Sun, Lun-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257677/
https://www.ncbi.nlm.nih.gov/pubmed/20877211
http://dx.doi.org/10.3390/molecules15096127