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Synthesis and Antiviral Bioactivity of Chiral Thioureas Containing Leucine and Phosphonate Moieties

A series of novel chiral thioureas 3a-n bearing leucine and phosphonate moieties were synthesized in excellent yields. The structures of the compounds were completely characterized by elemental analysis, IR,( 1)H-, (13)C-, (31)P- and (19)F-NMR spectral data. A half-leaf method was used to determine...

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Detalles Bibliográficos
Autores principales: Liu, Jingzi, Yang, Song, Li, Xiangyang, Fan, Huitao, Bhadury, Pinaki, Xu, Weiming, Wu, Jian, Wang,  Zhencao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257697/
https://www.ncbi.nlm.nih.gov/pubmed/20714289
http://dx.doi.org/10.3390/molecules15085112