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Generation and Development of RNA Ligase Ribozymes with Modular Architecture Through “Design and Selection”

In vitro selection with long random RNA libraries has been used as a powerful method to generate novel functional RNAs, although it often requires laborious structural analysis of isolated RNA molecules. Rational RNA design is an attractive alternative to avoid this laborious step, but rational desi...

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Detalles Bibliográficos
Autores principales: Fujita, Yuki, Ishikawa, Junya, Furuta, Hiroyuki, Ikawa, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257700/
https://www.ncbi.nlm.nih.gov/pubmed/22273983
http://dx.doi.org/10.3390/molecules15095850