Cargando…

Synthesis of Chiral Macrocyclic or Linear Pyridine Carboxamides from Pyridine-2,6-dicarbonyl Dichloride as Antimicrobial Agents

A series of chiral linear and macrocyclic bridged pyridines has been prepared starting from pyridine-2,6-dicarbonyl dichloride (2). The coupling of 1 with D-alanyl methyl ester gave 2,6-bis-D-alanyl pyridine methyl ester (3). Hydrazinolysis of 3 with hydrazine hydrate afforded bis-hydrazide 4. The l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Al-Salahi, Rashad A., Al-Omar, Mohamed A., Amr, Abd El-Galil E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257722/ https://www.ncbi.nlm.nih.gov/pubmed/20877246 http://dx.doi.org/10.3390/molecules15096588

Ejemplares similares

Synthesis of Some New Pyridine-2,6-carboxamide-derived Schiff Bases as Potential Antimicrobial Agents
por: Al-Omar, Mohamed A., et al.
Publicado: (2010)

6-Bromopyridine-2-carboxamide
por: Xue, Feng, et al.
Publicado: (2009)

2-Chloropyridine-3-carboxamide
por: Hua, Yu-Peng, et al.
Publicado: (2009)

Bis(μ(2)-pyridine-2-carboxamide oximato)bis[(pyridine-2-carboxamide oxime)zinc] dinitrate
por: Deng, Xiao-Hui, et al.
Publicado: (2011)

Crystal structure of 1,1′-(pyridine-2,6-diyl)bis[N-(pyridin-2-ylmethyl)methanaminium] dichloride dihydrate
por: Merabet, Layachi, et al.
Publicado: (2021)

Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates
por: El-Salam, Osama I. Abd, et al.
Publicado: (2012)

N-Hydroxypyridine-4-carboxamide
por: Wu, Qingkun, et al.
Publicado: (2011)

N-Butylpyridine-4-thiocarboxamide
por: Kavitha, T., et al.
Publicado: (2007)

Pyridine-3-carboxamide–telluric acid (1/1)
por: Fábry, Jan
Publicado: (2018)

Anticancer Activities of Newly Synthesized Chiral Macrocyclic Heptapeptide Candidates
por: Abo-Ghalia, Mohamed H., et al.
Publicado: (2020)

N-[2,6-Bis(1-methylethyl)phenyl]pyridine-4-carboxamide
por: Laramée, Baptiste, et al.
Publicado: (2012)

Synthesis and Biological Activities of Some New (N(α)-Dinicotinoyl)-bis-l-Leucyl Linear and Macrocyclic Peptides
por: Khayyat, Suzan, et al.
Publicado: (2014)

Pyridine Carboxamides Based on Sulfobetaines: Design, Reactivity, and Biological Activity
por: Kramarova, Eugene P., et al.
Publicado: (2022)

Crystal structures of N-(pyridin-2-ylmethyl)pyrazine-2-carboxamide (monoclinic polymorph) and N-(pyridin-4-ylmethyl)pyrazine-2-carboxamide
por: Cati, Dilovan S., et al.
Publicado: (2014)

Crystal structure of ammonium bis[(pyridin-2-yl)methyl]ammonium dichloride
por: Trischler, Aaron, et al.
Publicado: (2015)

trans-Tetrakis[N-(adamantan-1-yl)pyridine-4-carboxamide]dichloridomanganese(II)–N-(adamantan-1-yl)pyridine-4-carboxamide (1/2)
por: Wang, Ying-Chun
Publicado: (2012)

Crystal structures of three N-(pyridine-2-carbonyl)pyridine-2-carboxamides as potential ligands for supramolecular chemistry
por: Xu, Xiaowen, et al.
Publicado: (2021)

Highly enantioselective catalytic synthesis of chiral pyridines
por: Jumde, Ravindra P., et al.
Publicado: (2017)

Synthesis and Characterization of Macrocyclic Chiral Tröger’s Base Phenhomazine Candidates as Anticancer Agent
por: Ibrahim, Alhussein A., et al.
Publicado: (2021)

Synthesis and solid-state structures of a macrocyclic receptor based on the 2,6-bis(2-anilinoethynyl)pyridine scaffold
por: Engle, Jeffrey M., et al.
Publicado: (2014)

N-(2,6-Dichlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
por: Tu, Ni, et al.
Publicado: (2023)

Binary and ternary cocrystals of sulfa drug acetazolamide with pyridine carboxamides and cyclic amides
por: Bolla, Geetha, et al.
Publicado: (2016)

Discovery of novel pyridine carboxamides with antifungal activity as potential succinate dehydrogenase inhibitors
por: Yan, Zhongzhong, et al.
Publicado: (2022)

Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
por: Saeed, Saeed El-Sayed, et al.
Publicado: (2023)

Two coordination modes of Cu(II) in a binuclear complex with N-(pyridin-2-ylcarbonyl)pyridine-2-carboxamidate ligands
por: Campos-Gaxiola, José J., et al.
Publicado: (2012)

4-(Naphthalene-2-carboxamido)pyridin-1-ium thiocyanate–N-(pyridin-4-yl)naphthalene-2-carboxamide (1/1)
por: Saeed, Sohail, et al.
Publicado: (2012)

Tetrakis(2,6-diaminopyridinium) diphthalate 2,6-diaminopyridine
por: Al-Dajani, Mohammad T. M., et al.
Publicado: (2009)

4-Oxo-N-phenyl-1,4-dihydropyridine-3-carboxamide
por: Shu, Xi, et al.
Publicado: (2023)

Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehydrogenase-A
por: Amr, Abd El-Galil E., et al.
Publicado: (2020)

2,6-Dichloro-3-nitropyridine
por: Fun, Hoong-Kun, et al.
Publicado: (2011)

Synthesis of a New Series of Pyridine and Fused Pyridine Derivatives
por: Al-Issa, Siham AbdulRahman
Publicado: (2012)

Creatininium bis(pyridine-2,6-dicarboxylato)chromate(III) pyridine-2,6-dicarboxylic acid hexahydrate
por: Aghabozorg, Hossein, et al.
Publicado: (2008)

2-Methylsulfanyl-1,2,4-triazolo[1,5-a]quinazoline-5(4H)-thione
por: Al-Salahi, Rashad, et al.
Publicado: (2013)

[(Pyridine-2,6-dicarboxylato)copper(II)]-μ-(pyridine-2,6-dicarboxylato)-[bis(ethylenediamine)copper(II)]-μ-(pyridine-2,6-dicarboxylato)-[(pyridine-2,6-dicarboxylato)copper(II)] ethylenediamine monosolvate tetrahydrate
por: Shokooh Saljooghi, Amir, et al.
Publicado: (2012)

Methyl 2-{6-[(1-methoxy-1-oxopropan-2-yl)aminocarbonyl]pyridine-2-carboxamido}propanoate
por: Al-Omar, Mohamed A., et al.
Publicado: (2012)

Two N,N′-bis(pyridin-4-yl)pyridine-2,6-dicarboxamide coordination compounds
por: Guo, Yue-Xin, et al.
Publicado: (2018)

Accessing Diverse Pyridine-Based Macrocyclic Peptides by a Two-Site Recognition Pathway
por: Nguyen, Dinh T., et al.
Publicado: (2022)

The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative Leishmania Species †
por: Martín-Montes, Álvaro, et al.
Publicado: (2023)

N-(1H-1,2,4-Triazol-5-yl)pyridine-2-carboxamide
por: Miao, Jing, et al.
Publicado: (2009)

Bis[N-(4-chlorophenyl)pyridine-3-carboxamide]silver(I) nitrate
por: Shi, Chun-Yue, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_cplbk93fkp1nc3bef9ha6h9bpo