2-(Penta-1,3-diynyl)-5-(3,4-dihydroxybut-1-ynyl)thiophene, a Novel NQO1 Inducing Agent from Echinops grijsii Hance

A natural alkynol group-substituted thiophene, 2-(penta-1,3-diynyl)-5-(3,4-dihydroxybut-1-ynyl)-thiophene (PDDYT), was isolated from the roots of Echinops grijsii Hance. It possessed potent NAD(P)H: quinone oxidoreductase1 (NQO1) inducing activity and could activate Keap1-Nrf2 pathway effectively in...

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Detalles Bibliográficos
Autores principales: Shi, Jing, Zhang, Xiaoyu, Jiang, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257798/
https://www.ncbi.nlm.nih.gov/pubmed/20714298
http://dx.doi.org/10.3390/molecules15085273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257798/
https://www.ncbi.nlm.nih.gov/pubmed/20714298
http://dx.doi.org/10.3390/molecules15085273

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