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Dopamine neurons drive fear extinction learning by signaling the omission of expected aversive outcomes

Extinction of fear responses is critical for adaptive behavior and deficits in this form of safety learning are hallmark of anxiety disorders. However, the neuronal mechanisms that initiate extinction learning are largely unknown. Here we show, using single-unit electrophysiology and cell-type speci...

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Detalles Bibliográficos
Autores principales: Salinas-Hernández, Ximena I, Vogel, Pascal, Betz, Sebastian, Kalisch, Raffael, Sigurdsson, Torfi, Duvarci, Sevil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257816/
https://www.ncbi.nlm.nih.gov/pubmed/30421719
http://dx.doi.org/10.7554/eLife.38818