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sTLR4/sMD-2 complex alleviates LPS-induced acute lung injury by inhibiting pro-inflammatory cytokines and chemokine CXCL1 expression

Activation of Toll-like receptor 4 (TLR4) and its accessory proteins myeloid differentiation protein 2 (MD-2) can trigger immune and inflammatory activities, and contribute to developing chronic inflammatory diseases. The formation of the TLR4/MD-2 complex after binding to lipopolysaccharide (LPS) l...

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Detalles Bibliográficos
Autores principales: Meng, Jie, Zou, Yan, Chen, Jifei, Qin, Fengxian, Chen, Xiang, Chen, Xiaoli, Dai, Shengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257829/
https://www.ncbi.nlm.nih.gov/pubmed/30542414
http://dx.doi.org/10.3892/etm.2018.6746