Cargando…

lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression

MicroRNA (miR)-214 has been demonstrated to suppress gluconeogenesis by targeting activating transcription factor 4 (ATF4), which regulates gluconeogenesis by affecting the transcriptional activity of forkhead box protein O1 (FoxO1). Our previous study revealed that the upregulation of maternally ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xiang, Li, Hongqi, Wu, Yuanbo, Zhou, Jian, Yang, Guangwei, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257836/
https://www.ncbi.nlm.nih.gov/pubmed/30431065
http://dx.doi.org/10.3892/ijmm.2018.3975