Cargando…

Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry

Endometriosis is a well-known risk factor for ovarian cancer. The genetic changes that characterise endometriosis are poorly understood; however, the mechanistic target of rapamycin (mTOR) pathway is involved. In this study, we investigated the expression of key mTOR components in endometriosis and...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogers-Broadway, Karly-Rai, Kumar, Juhi, Sisu, Cristina, Wander, Gurleen, Mazey, Emily, Jeyaneethi, Jeyarooban, Pados, George, Tsolakidis, Dimitris, Klonos, Eleftherios, Grunt, Thomas, Hall, Marcia, Chatterjee, Jayanta, Karteris, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257843/
https://www.ncbi.nlm.nih.gov/pubmed/30387804
http://dx.doi.org/10.3892/ijmm.2018.3967