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Galectin-1 gene silencing inhibits the activation and proliferation but induces the apoptosis of hepatic stellate cells from mice with liver fibrosis

Liver fibrosis is a serious threat to human health, and there is currently no effective clinical drug for treatment of the disease. Although Galectin-1 is effective, its role in liver function, inflammation, matrix metalloproteinases and the activation of hepatic stellate cells (HSCs) remains to be...

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Detalles Bibliográficos
Autores principales: Jiang, Zhi-Jun, Shen, Qing-Hua, Chen, Hai-Yong, Yang, Zhe, Shuai, Ming-Qi, Zheng, Shu-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257862/
https://www.ncbi.nlm.nih.gov/pubmed/30365068
http://dx.doi.org/10.3892/ijmm.2018.3950