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Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition

The present study aimed to determine whether isorhamnetin (Isor), a natural antioxidant polyphenol, has antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis. A C57 mouse model of pulmonary fibrosis was established by intraperitoneal injection of a single dose of bleomycin (...

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Detalles Bibliográficos
Autores principales: Zheng, Qing, Tong, Ming, Ou, Baiqing, Liu, Cuizhong, Hu, Changping, Yang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257865/
https://www.ncbi.nlm.nih.gov/pubmed/30387812
http://dx.doi.org/10.3892/ijmm.2018.3965