Cargando…

Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition

The present study aimed to determine whether isorhamnetin (Isor), a natural antioxidant polyphenol, has antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis. A C57 mouse model of pulmonary fibrosis was established by intraperitoneal injection of a single dose of bleomycin (...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Qing, Tong, Ming, Ou, Baiqing, Liu, Cuizhong, Hu, Changping, Yang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257865/ https://www.ncbi.nlm.nih.gov/pubmed/30387812 http://dx.doi.org/10.3892/ijmm.2018.3965

Ejemplares similares

Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Zhao, Hui, et al.
Publicado: (2014)

Tauroursodeoxycholic acid alleviates pulmonary endoplasmic reticulum stress and epithelial-mesenchymal transition in bleomycin-induced lung fibrosis
por: Tong, Bin, et al.
Publicado: (2021)

Correction: Melatonin Inhibits Endoplasmic Reticulum Stress and Epithelial-Mesenchymal Transition during Bleomycin-Induced Pulmonary Fibrosis in Mice
Publicado: (2015)

Endoplasmic reticulum stress promotes epithelial-mesenchymal transition via the PERK signaling pathway in paraquat-induced pulmonary fibrosis
por: Meng, Xiaoxiao, et al.
Publicado: (2021)

Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation
por: Guan, Ruijuan, et al.
Publicado: (2016)

Calpain inhibition attenuates bleomycin-induced pulmonary fibrosis via switching the development of epithelial-mesenchymal transition
por: Liu, Yuan, et al.
Publicado: (2018)

Hypoxia-Induced Epithelial-Mesenchymal Transition Is Involved in Bleomycin-Induced Lung Fibrosis
por: Guo, Liang, et al.
Publicado: (2015)

Endoplasmic reticulum stress regulates epithelial-mesenchymal transition in human lens epithelial cells
por: Zhou, Sheng, et al.
Publicado: (2020)

Sorafenib ameliorates bleomycin-induced pulmonary fibrosis: potential roles in the inhibition of epithelial–mesenchymal transition and fibroblast activation
por: Chen, Y-L, et al.
Publicado: (2013)

Astragaloside IV modulates TGF‐β1‐dependent epithelial‐mesenchymal transition in bleomycin‐induced pulmonary fibrosis
por: Qian, Weibin, et al.
Publicado: (2018)

NecroX-5 ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3-mediated epithelial–mesenchymal transition
por: Min, Li, et al.
Publicado: (2022)

Bleomycin induces epithelial-to-mesenchymal transition via bFGF/PI3K/ESRP1 signaling in pulmonary fibrosis
por: Weng, Chang-Mei, et al.
Publicado: (2020)

2-aminopurine suppresses the TGF-β1-induced epithelial–mesenchymal transition and attenuates bleomycin-induced pulmonary fibrosis
por: Weng, Dong, et al.
Publicado: (2018)

Vincamine Ameliorates Epithelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis in Rats; Targeting TGF-β/MAPK/Snai1 Pathway
por: Alaaeldin, Rania, et al.
Publicado: (2023)

Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Chang, Kai-Wei, et al.
Publicado: (2021)

Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway
por: Li, Jiang, et al.
Publicado: (2023)

Epithelial-Mesenchymal Transition Induces Endoplasmic-Reticulum-Stress Response in Human Colorectal Tumor Cells
por: Zeindl-Eberhart, Evelyn, et al.
Publicado: (2014)

The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition
por: Feng, Yu-xiong, et al.
Publicado: (2014)

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
por: Zhou, Xiao-Ming, et al.
Publicado: (2017)

Hydrogen Sulfide Inhibits Bronchial Epithelial Cell Epithelial Mesenchymal Transition Through Regulating Endoplasm Reticulum Stress
por: Lin, Fan, et al.
Publicado: (2022)

Bleomycin-enhanced alternative splicing of fibroblast growth factor receptor 2 induces epithelial to mesenchymal transition in lung fibrosis
por: Chen, Kui-Jun, et al.
Publicado: (2018)

Anti-Obesity Effects of Isorhamnetin and Isorhamnetin Conjugates
por: González-Arceo, Maitane, et al.
Publicado: (2022)

PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo
por: Sun, Hu-Nan, et al.
Publicado: (2023)

IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells
por: Gong, Ling, et al.
Publicado: (2020)

Epithelial–Mesenchymal Transition in the Pathogenesis of Idiopathic Pulmonary Fibrosis
por: Salton, Francesco, et al.
Publicado: (2019)

Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis
por: Singh, Shweta, et al.
Publicado: (2020)

Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway
por: Li, Li‐Fu, et al.
Publicado: (2017)

Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-β1/Smad Pathway and Epithelial to Mesenchymal Transition
por: Meng, Lihong, et al.
Publicado: (2019)

Mesenchymal Stem Cells Inhibit Epithelial-to-Mesenchymal Transition by Modulating the IRE1α Branch of the Endoplasmic Reticulum Stress Response
por: Luo, Ruixi, et al.
Publicado: (2023)

Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis
por: Ganbold, Munkhzul, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells
por: Yoon, Sarah, et al.
Publicado: (2021)

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
por: Kyung, Sun Young, et al.
Publicado: (2018)

Role of Ferroptosis in Regulating the Epithelial–Mesenchymal Transition in Pulmonary Fibrosis
por: Ling, Hong, et al.
Publicado: (2023)

Hypoxia-preconditioned mesenchymal stem cells attenuate bleomycin-induced pulmonary fibrosis
por: Lan, Ying-Wei, et al.
Publicado: (2015)

Lost in Translation: Endoplasmic Reticulum–Mitochondria Crosstalk in Idiopathic Pulmonary Fibrosis
por: Bueno, Marta, et al.
Publicado: (2020)

Immune Mechanisms of Pulmonary Fibrosis with Bleomycin
por: Ishida, Yuko, et al.
Publicado: (2023)

Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence
por: Zhang, Li, et al.
Publicado: (2020)

Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an α-smooth muscle actin-Cre transgenic mouse
por: Wu, Zhuang, et al.
Publicado: (2007)

Induced Pluripotent Stem Cells Inhibit Bleomycin-Induced Pulmonary Fibrosis in Mice through Suppressing TGF-β1/Smad-Mediated Epithelial to Mesenchymal Transition
por: Zhou, Yan, et al.
Publicado: (2016)

Vitamin D deficiency exacerbates bleomycin-induced pulmonary fibrosis partially through aggravating TGF-β/Smad2/3-mediated epithelial-mesenchymal transition
por: Li, Se-Ruo, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3as93074maofdcvvcin8d1ifs0