Keratocytes Generate High Integrin Tension at the Trailing Edge to Mediate Rear De-adhesion during Rapid Cell Migration

Rapid cell migration requires efficient rear de-adhesion. It remains undetermined whether cells mechanically detach or biochemically disassemble integrin-mediated rear adhesion sites in highly motile cells such as keratocytes. Using molecular tension sensor, we calibrated and mapped integrin tension...

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Detalles Bibliográficos
Autores principales: Zhao, Yuanchang, Wang, Yongliang, Sarkar, Anwesha, Wang, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257914/
https://www.ncbi.nlm.nih.gov/pubmed/30472533
http://dx.doi.org/10.1016/j.isci.2018.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257914/
https://www.ncbi.nlm.nih.gov/pubmed/30472533
http://dx.doi.org/10.1016/j.isci.2018.11.016

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