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AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase
The expression of hTERT in tumor cells contributes to oncogenic transformation by promoting immortalization. For this reason, hTERT is one of the major targets for cancer therapy, and an efficient method to downregulate hTERT expression is required for treatment of hTERT-positive cancer. In this rep...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257937/ https://www.ncbi.nlm.nih.gov/pubmed/30475873 http://dx.doi.org/10.1371/journal.pone.0207864 |