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AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase

The expression of hTERT in tumor cells contributes to oncogenic transformation by promoting immortalization. For this reason, hTERT is one of the major targets for cancer therapy, and an efficient method to downregulate hTERT expression is required for treatment of hTERT-positive cancer. In this rep...

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Detalles Bibliográficos
Autores principales: Jo, Daum, Park, Rackhyun, Kim, Hyunju, Jang, Minsu, Lee, Eun-Ju, Jang, Ik-Soon, Park, Junsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257937/
https://www.ncbi.nlm.nih.gov/pubmed/30475873
http://dx.doi.org/10.1371/journal.pone.0207864