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Migration through a small pore disrupts inactive chromatin organization in neutrophil-like cells

BACKGROUND: Mammalian cells are flexible and can rapidly change shape when they contract, adhere, or migrate. The nucleus must be stiff enough to withstand cytoskeletal forces, but flexible enough to remodel as the cell changes shape. This is particularly important for cells migrating through confin...

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Detalles Bibliográficos
Autores principales: Jacobson, Elsie C., Perry, Jo K., Long, David S., Olins, Ada L., Olins, Donald E., Wright, Bryon E., Vickers, Mark H., O’Sullivan, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257957/
https://www.ncbi.nlm.nih.gov/pubmed/30477489
http://dx.doi.org/10.1186/s12915-018-0608-2