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Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

Various mutations in the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene are associated with neurodevelopmental and neuropsychiatric disorders. Thus far, synaptic abnormalities in multiple brain regions, including the hippocampus, prefrontal cortex, striatum, and ventral tegmental area, have...

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Detalles Bibliográficos
Autores principales: Jin, Chunmei, Kang, Hyojin, Kim, Shinhyun, Zhang, Yinhua, Lee, Yeunkum, Kim, Yoonhee, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257967/
https://www.ncbi.nlm.nih.gov/pubmed/30482234
http://dx.doi.org/10.1186/s13041-018-0413-4