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Molecular and biochemical characterization of key enzymes in the cysteine and serine metabolic pathways of Acanthamoeba castellanii

BACKGROUND: Acanthamoeba spp. can cause serious human infections, including Acanthamoeba keratitis, granulomatous amoebic encephalitis and cutaneous acanthamoebiasis. Cysteine biosynthesis and the L-serine metabolic pathway play important roles in the energy metabolism of Acanthamoeba spp. However,...

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Detalles Bibliográficos
Autores principales: Wu, Duo, Feng, Meng, Wang, Zhi-xin, Qiao, Ke, Tachibana, Hiroshi, Cheng, Xun-jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257972/
https://www.ncbi.nlm.nih.gov/pubmed/30477573
http://dx.doi.org/10.1186/s13071-018-3188-7