TRPM7 overexpression enhances the cancer stem cell-like and metastatic phenotypes of lung cancer through modulation of the Hsp90α/uPA/MMP2 signaling pathway

BACKGROUND: Waixenicin A, a bioactive extract of soft coral Sarcothelia edmondsoni, has been shown to be anti-neoplastic. However, its mechanisms of action remain unclear. Cancer stem cells (CSCs) and associated stemness factors are implicated in lung cancer. Here, we investigated the role of Waixen...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Xu, Shao-Hua, Chen, Zhao, Zeng, Qing-Xin, Li, Zhi-Jun, Chen, Zhou-Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258145/
https://www.ncbi.nlm.nih.gov/pubmed/30477473
http://dx.doi.org/10.1186/s12885-018-5050-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258145/
https://www.ncbi.nlm.nih.gov/pubmed/30477473
http://dx.doi.org/10.1186/s12885-018-5050-x

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