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Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer

BACKGROUND: Cancer-associated fibroblasts (CAFs) are activated fibroblasts associated with cancer. They have an important role in tumor growth and metastasis. Artemisinin (ART) is a sesquiterpene lactone extracted from Chinese herb qinghao, and artemether (ARM), artesunate (ARS) and dihydroartemisin...

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Detalles Bibliográficos
Autores principales: Yao, Yuyuan, Guo, Qinglong, Cao, Yue, Qiu, Yangmin, Tan, Renxiang, Yu, Zhou, Zhou, Yuxin, Lu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258160/
https://www.ncbi.nlm.nih.gov/pubmed/30477536
http://dx.doi.org/10.1186/s13046-018-0960-7