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Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF-β signaling in breast cancer
BACKGROUND: Cancer-associated fibroblasts (CAFs) are activated fibroblasts associated with cancer. They have an important role in tumor growth and metastasis. Artemisinin (ART) is a sesquiterpene lactone extracted from Chinese herb qinghao, and artemether (ARM), artesunate (ARS) and dihydroartemisin...
Autores principales: | Yao, Yuyuan, Guo, Qinglong, Cao, Yue, Qiu, Yangmin, Tan, Renxiang, Yu, Zhou, Zhou, Yuxin, Lu, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258160/ https://www.ncbi.nlm.nih.gov/pubmed/30477536 http://dx.doi.org/10.1186/s13046-018-0960-7 |
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