Brain hyperserotonemia causes autism-relevant social deficits in mice

BACKGROUND: Hyperserotonemia in the brain is suspected to be an endophenotype of autism spectrum disorder (ASD). Reducing serotonin levels in the brain through modulation of serotonin transporter function may improve ASD symptoms. METHODS: We analyzed behavior and gene expression to unveil the causa...

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Detalles Bibliográficos
Autores principales: Tanaka, Miho, Sato, Atsushi, Kasai, Shinya, Hagino, Yoko, Kotajima-Murakami, Hiroko, Kashii, Hirofumi, Takamatsu, Yukio, Nishito, Yasumasa, Inagaki, Masumi, Mizuguchi, Masashi, Hall, F. Scott, Uhl, George R., Murphy, Dennis, Sora, Ichiro, Ikeda, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258166/
https://www.ncbi.nlm.nih.gov/pubmed/30498565
http://dx.doi.org/10.1186/s13229-018-0243-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258166/
https://www.ncbi.nlm.nih.gov/pubmed/30498565
http://dx.doi.org/10.1186/s13229-018-0243-3

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