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Differential open chromatin profile and transcriptomic signature define depot-specific human subcutaneous preadipocytes: primary outcomes

BACKGROUND: Increased lower body fat is associated with reduced cardiometabolic risk. The molecular basis for depot-specific differences in gluteofemoral (GF) compared with abdominal (A) subcutaneous adipocyte function is poorly understood. In the current report, we used a combination of Assay for T...

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Detalles Bibliográficos
Autores principales: Divoux, Adeline, Sandor, Katalin, Bojcsuk, Dora, Talukder, Amlan, Li, Xiaoman, Balint, Balint L., Osborne, Timothy F., Smith, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258289/
https://www.ncbi.nlm.nih.gov/pubmed/30477572
http://dx.doi.org/10.1186/s13148-018-0582-0