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Suppression of hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia following systemic administration of lutein via inhibition of cyclooxygenase-2 cascade signaling

INTRODUCTION: Lutein is a dietary constituent known to inhibit inflammation; however, its effect on nociceptive neuron-associated hyperalgesia remains to be determined. The present study therefore investigated under in vivo conditions whether administration of lutein attenuates the inflammation-indu...

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Detalles Bibliográficos
Autores principales: Syoji, Yumiko, Kobayashi, Ryota, Miyamura, Nako, Hirohara, Tsukasa, Kubota, Yoshiko, Uotsu, Nobuo, Yui, Kei, Shimazu, Yoshihito, Takeda, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258298/
https://www.ncbi.nlm.nih.gov/pubmed/30498399
http://dx.doi.org/10.1186/s12950-018-0200-0