Early-Life Antibiotics Attenuate Regulatory T Cell Generation and Increase the Severity of Murine House Dust Mite-Induced Asthma

INTRODUCTION: Early-life exposure to antibiotics (ABX) has been linked to increases in asthma severity and prevalence in both children and laboratory animals. We explored the immunologic mechanisms behind this association using a mouse model of house dust mite (HDM)-induced asthma and early-life ABX...

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Detalles Bibliográficos
Autores principales: Adami, Alexander J., Bracken, Sonali J., Guernsey, Linda A., Rafti, Ektor, Maas, Kendra R., Graf, Joerg, Matson, Adam P., Thrall, Roger S., Schramm, Craig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258300/
https://www.ncbi.nlm.nih.gov/pubmed/29967529
http://dx.doi.org/10.1038/s41390-018-0031-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258300/
https://www.ncbi.nlm.nih.gov/pubmed/29967529
http://dx.doi.org/10.1038/s41390-018-0031-y

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