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Early-Life Antibiotics Attenuate Regulatory T Cell Generation and Increase the Severity of Murine House Dust Mite-Induced Asthma
INTRODUCTION: Early-life exposure to antibiotics (ABX) has been linked to increases in asthma severity and prevalence in both children and laboratory animals. We explored the immunologic mechanisms behind this association using a mouse model of house dust mite (HDM)-induced asthma and early-life ABX...
Autores principales: | Adami, Alexander J., Bracken, Sonali J., Guernsey, Linda A., Rafti, Ektor, Maas, Kendra R., Graf, Joerg, Matson, Adam P., Thrall, Roger S., Schramm, Craig M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258300/ https://www.ncbi.nlm.nih.gov/pubmed/29967529 http://dx.doi.org/10.1038/s41390-018-0031-y |
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