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Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in E. coli
Chaperone-usher pathway (CUP) pili are extracellular proteinaceous fibers ubiquitously found on Gram-negative bacteria, and mediate host-pathogen interactions and biofilm formation critical in pathogenesis in numerous human diseases(1). During pilus assembly an outer membrane (OM) macromolecular mac...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258349/ https://www.ncbi.nlm.nih.gov/pubmed/30275511 http://dx.doi.org/10.1038/s41564-018-0255-y |