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Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in E. coli

Chaperone-usher pathway (CUP) pili are extracellular proteinaceous fibers ubiquitously found on Gram-negative bacteria, and mediate host-pathogen interactions and biofilm formation critical in pathogenesis in numerous human diseases(1). During pilus assembly an outer membrane (OM) macromolecular mac...

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Detalles Bibliográficos
Autores principales: Omattage, Natalie S., Deng, Zengqin, Pinkner, Jerome S., Dodson, Karen W., Almqvist, Fredrik, Yuan, Peng, Hultgren, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258349/
https://www.ncbi.nlm.nih.gov/pubmed/30275511
http://dx.doi.org/10.1038/s41564-018-0255-y

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